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Effect of Serial Systemic and Intratumoral Injections of Oncolytic ZIKV(BR) in Mice Bearing Embryonal CNS Tumors

The Zika virus (ZIKV) has shown a promising oncolytic effect against embryonal CNS tumors. However, studies on the effect of different administration routes and the ideal viral load in preclinical models are highly relevant aiming for treatment safety and efficiency. Here, we investigated the effect...

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Detalles Bibliográficos
Autores principales: Ferreira, Raiane Oliveira, Granha, Isabela, Ferreira, Rodolfo Sanches, Bueno, Heloisa de Siqueira, Okamoto, Oswaldo Keith, Kaid, Carolini, Zatz, Mayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541080/
https://www.ncbi.nlm.nih.gov/pubmed/34696533
http://dx.doi.org/10.3390/v13102103