Synthesis, Characterization and In Vitro Evaluation of Hybrid Monomeric Peptides Suited for Multimodal Imaging by PET/OI: Extending the Concept of Charge—Cell Binding Correlation

In the context of hybrid multimodal imaging agents for gastrin releasing peptide receptor (GRPR) targeting, a correlation between the net charge and the receptor affinity of the agents was recently found. In particular, a decrease in in vitro GRPR binding affinity was observed in case of an increasi...

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Detalles Bibliográficos
Autores principales: Maspero, Marco, Cheng, Xia, von Kiedrowski, Valeska, Dallanoce, Clelia, Wängler, Björn, Hübner, Ralph, Wängler, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541144/
https://www.ncbi.nlm.nih.gov/pubmed/34681213
http://dx.doi.org/10.3390/ph14100989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541144/
https://www.ncbi.nlm.nih.gov/pubmed/34681213
http://dx.doi.org/10.3390/ph14100989

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