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Synthesis and Bioactivity of Ancorinoside B, a Marine Diglycosyl Tetramic Acid

The sponge metabolite ancorinoside B was prepared for the first time in 16 steps and 4% yield. It features a β-d-galactopyranosyl-(1→4)-β-d-glucuronic acid tethered to a d-aspartic acid-derived tetramic acid. Key steps were the synthesis of a fully protected d-lactose derived thioglycoside, its atta...

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Detalles Bibliográficos
Autores principales: Soliga, Kevin J., Bär, Sofia I., Oberhuber, Natalie, Zeng, Haoxuan, Schrey, Hedda, Schobert, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541288/
https://www.ncbi.nlm.nih.gov/pubmed/34677482
http://dx.doi.org/10.3390/md19100583