Effects of Impurities from Sugar Excipient on Filtrate Flux during Ultrafiltration and Diafiltration Process

Sugar excipients such as sucrose and maltose are widely used for biopharmaceutical formulation to improve protein stability and to ensure isotonicity for administration. However, according to recent literature, pharmaceutical-grade sucrose contained nanoparticulate impurities (NPIs) that result in p...

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Detalles Bibliográficos
Autores principales: Lee, Jieun, Na, Jiwon, Baek, Youngbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541299/
https://www.ncbi.nlm.nih.gov/pubmed/34677543
http://dx.doi.org/10.3390/membranes11100775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541299/
https://www.ncbi.nlm.nih.gov/pubmed/34677543
http://dx.doi.org/10.3390/membranes11100775

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