Cellular Toxicity Mechanisms and the Role of Autophagy in Pt(IV) Prodrug-Loaded Ultrasmall Iron Oxide Nanoparticles Used for Enhanced Drug Delivery

Ultrasmall iron oxide nanoparticles (<10 nm) were loaded with cis-diamminetetrachloroplatinum (IV), a cisplatin (II) prodrug, and used as an efficient nanodelivery system in cell models. To gain further insight into their behavior in ovarian cancer cells, the level of cellular incorporation as we...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Romero, L., Rivas-García, L., Sánchez-González, C., Llopis, J., Blanco, E., Montes-Bayón, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541321/
https://www.ncbi.nlm.nih.gov/pubmed/34684023
http://dx.doi.org/10.3390/pharmaceutics13101730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541321/
https://www.ncbi.nlm.nih.gov/pubmed/34684023
http://dx.doi.org/10.3390/pharmaceutics13101730

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