The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation

The presence of latent human immunodeficiency virus (HIV) reservoirs is a major obstacle to a cure. The “shock and kill” therapy is based on the concept that latent reservoirs in HIV carriers with antiretroviral therapy are reactivated by latency-reversing agents (LRAs), followed by elimination due...

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Detalles Bibliográficos
Autores principales: Washizaki, Ayaka, Murata, Megumi, Seki, Yohei, Kikumori, Masayuki, Tang, Yinpui, Tan, Weikeat, Wardani, Nadita P., Irie, Kazuhiro, Akari, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541327/
https://www.ncbi.nlm.nih.gov/pubmed/34696466
http://dx.doi.org/10.3390/v13102037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541327/
https://www.ncbi.nlm.nih.gov/pubmed/34696466
http://dx.doi.org/10.3390/v13102037

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