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Lipase Assisted (S)-Ketoprofen Resolution from Commercially Available Racemic Mixture

Ketoprofen is a commercially available drug sold as a racemic mixture that belongs to the family of non-steroidal anti-inflammatory drugs known as profens. It has been demonstrated (in vitro) that (S)-ketoprofen is around 160 times more potent than its enantiomer (R)-ketoprofen, while accumulation o...

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Detalles Bibliográficos
Autores principales: Estrada-Valenzuela, Daniela, Ramos-Sánchez, Víctor H., Zaragoza-Galán, Gerardo, Espinoza-Hicks, Jose C., Bugarin, Alejandro, Chávez-Flores, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541352/
https://www.ncbi.nlm.nih.gov/pubmed/34681221
http://dx.doi.org/10.3390/ph14100996