AS1411 Aptamer Linked to DNA Nanostructures Diverts Its Traffic Inside Cancer Cells and Improves Its Therapeutic Efficacy

The nucleolin-binding G-quadruplex AS1411 aptamer has been widely used for cancer therapy and diagnosis and linked to nanoparticles for its selective targeting activity. We applied a computational and experimental integrated approach to study the effect of engineering AS1411 aptamer on an octahedral...

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Detalles Bibliográficos
Autores principales: Vindigni, Giulia, Raniolo, Sofia, Iacovelli, Federico, Unida, Valeria, Stolfi, Carmine, Desideri, Alessandro, Biocca, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541364/
https://www.ncbi.nlm.nih.gov/pubmed/34683964
http://dx.doi.org/10.3390/pharmaceutics13101671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541364/
https://www.ncbi.nlm.nih.gov/pubmed/34683964
http://dx.doi.org/10.3390/pharmaceutics13101671

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