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Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice

In this study we looked for the main protein pathway regulators which were responsible for the therapeutic impact on colon cancers when combining magnetic hyperthermia with the chemotherapeutic agent 5-fluorouracil (5FU). To this end, chitosan-coated magnetic nanoparticles (MNP) functionalized with...

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Detalles Bibliográficos
Autores principales: Dabaghi, Mohammad, Rasa, Seyed Mohammad Mahdi, Cirri, Emilio, Ori, Alessandro, Neri, Francesco, Quaas, Rainer, Hilger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541380/
https://www.ncbi.nlm.nih.gov/pubmed/34683917
http://dx.doi.org/10.3390/pharmaceutics13101625