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Gentamicin Population Pharmacokinetics in Pediatric Patients—A Prospective Study with Data Analysis Using the saemix Package in R

The aminoglycoside gentamicin is used for the empirical treatment of pediatric infections. It has a narrow therapeutic window. In this prospective study at University Children’s Hospital Zurich, Switzerland, we aimed to characterize the pharmacokinetics of gentamicin in pediatric patients and predic...

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Detalles Bibliográficos
Autores principales: Paioni, Paolo, Jäggi, Vera F., Tilen, Romy, Seiler, Michelle, Baumann, Philipp, Bräm, Dominic S., Jetzer, Carole, Haid, Robin T. U., Goetschi, Aljoscha N., Goers, Roland, Müller, Daniel, Coman Schmid, Diana, Meyer zu Schwabedissen, Henriette E., Rinn, Bernd, Berger, Christoph, Krämer, Stefanie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541459/
https://www.ncbi.nlm.nih.gov/pubmed/34683889
http://dx.doi.org/10.3390/pharmaceutics13101596