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Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic Conditions

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor. The median survival rate from diagnosis ranges from 15 to 17 months because the tumor is resistant to most therapeutic strategies. GBM exhibits microvascular hyperplasia and pronounced necrosis triggered by hypox...

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Detalles Bibliográficos
Autores principales: Sita, Giulia, Graziosi, Agnese, Hrelia, Patrizia, Morroni, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541491/
https://www.ncbi.nlm.nih.gov/pubmed/34681862
http://dx.doi.org/10.3390/ijms222011201