Modular Synthesis and Antiproliferative Activity of New Dihydro-1H-pyrazolo[1,3-b]pyridine Embelin Derivatives

A set of new dihydro-1H-pyrazolo[1,3-b]pyridine and pyrazolo[1,3-b]pyridine embelin derivatives was synthesized through a multicomponent reaction from natural embelin, 3-substituted-5-aminopyrazoles and aldehydes. The synthesized compounds were evaluated against three hematologic tumor cell lines, H...

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Detalles Bibliográficos
Autores principales: Martín-Acosta, Pedro, Amesty, Ángel, Guerra-Rodríguez, Miguel, Guerra, Borja, Fernández-Pérez, Leandro, Estévez-Braun, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541493/
https://www.ncbi.nlm.nih.gov/pubmed/34681250
http://dx.doi.org/10.3390/ph14101026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541493/
https://www.ncbi.nlm.nih.gov/pubmed/34681250
http://dx.doi.org/10.3390/ph14101026

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