Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents

A new series of di-spirooxindole analogs, engrafted with oxindole and cyclohexanone moieties, were synthesized. Initially, azomethine ylides were generated via reaction of the substituted isatins 3a–f (isatin, 3a, 6-chloroisatin, 3b, 5-fluoroisatin, 3c, 5-nitroisatin, 3d, 5-methoxyisatin, 3e, and 5-...

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Detalles Bibliográficos
Autores principales: Al-Majid, Abdullah Mohammed, Ali, M., Islam, Mohammad Shahidul, Alshahrani, Saeed, Alamary, Abdullah Saleh, Yousuf, Sammer, Choudhary, M. Iqbal, Barakat, Assem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541513/
https://www.ncbi.nlm.nih.gov/pubmed/34684885
http://dx.doi.org/10.3390/molecules26206305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541513/
https://www.ncbi.nlm.nih.gov/pubmed/34684885
http://dx.doi.org/10.3390/molecules26206305

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