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Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents
A new series of di-spirooxindole analogs, engrafted with oxindole and cyclohexanone moieties, were synthesized. Initially, azomethine ylides were generated via reaction of the substituted isatins 3a–f (isatin, 3a, 6-chloroisatin, 3b, 5-fluoroisatin, 3c, 5-nitroisatin, 3d, 5-methoxyisatin, 3e, and 5-...
Autores principales: | Al-Majid, Abdullah Mohammed, Ali, M., Islam, Mohammad Shahidul, Alshahrani, Saeed, Alamary, Abdullah Saleh, Yousuf, Sammer, Choudhary, M. Iqbal, Barakat, Assem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541513/ https://www.ncbi.nlm.nih.gov/pubmed/34684885 http://dx.doi.org/10.3390/molecules26206305 |
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