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Histone Deacetylase Inhibition Regulates Lipid Homeostasis in a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disorder of the motor system. While the etiology is still incompletely understood, defects in metabolism act as a major contributor to the disease progression. Recently, histone deacetylase (HDAC) inhibition using ACY-73...

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Detalles Bibliográficos
Autores principales: Burg, Thibaut, Rossaert, Elisabeth, Moisse, Matthieu, Van Damme, Philip, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541517/
https://www.ncbi.nlm.nih.gov/pubmed/34681883
http://dx.doi.org/10.3390/ijms222011224