Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors

A new series of quinoline-based benzenesulfonamides (QBS) were developed as potential carbonic anhydrase inhibitors (CAIs). The target QBS CAIs is based on the 4-anilinoquinoline scaffold where the primary sulphonamide functionality was grafted at C4 of the anilino moiety as a zinc anchoring group (...

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Detalles Bibliográficos
Autores principales: Shaldam, Moataz, Nocentini, Alessio, Elsayed, Zainab M., Ibrahim, Tamer M., Salem, Rofaida, El-Domany, Ramadan A., Capasso, Clemente, Supuran, Claudiu T., Eldehna, Wagdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541628/
https://www.ncbi.nlm.nih.gov/pubmed/34681794
http://dx.doi.org/10.3390/ijms222011119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541628/
https://www.ncbi.nlm.nih.gov/pubmed/34681794
http://dx.doi.org/10.3390/ijms222011119

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