Encapsulation of Large-Size Plasmids in PLGA Nanoparticles for Gene Editing: Comparison of Three Different Synthesis Methods

The development of new gene-editing technologies has fostered the need for efficient and safe vectors capable of encapsulating large nucleic acids. In this work we evaluate the synthesis of large-size plasmid-loaded PLGA nanoparticles by double emulsion (considering batch ultrasound and microfluidic...

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Detalles Bibliográficos
Autores principales: López-Royo, Tresa, Sebastián, Víctor, Moreno-Martínez, Laura, Uson, Laura, Yus, Cristina, Alejo, Teresa, Zaragoza, Pilar, Osta, Rosario, Arruebo, Manuel, Manzano, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541650/
https://www.ncbi.nlm.nih.gov/pubmed/34685164
http://dx.doi.org/10.3390/nano11102723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541650/
https://www.ncbi.nlm.nih.gov/pubmed/34685164
http://dx.doi.org/10.3390/nano11102723

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