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The Expression and Localisation of G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels Is Differentially Altered in the Hippocampus of Two Mouse Models of Alzheimer’s Disease

G protein-gated inwardly rectifying K(+) (GIRK) channels are the main targets controlling excitability and synaptic plasticity on hippocampal neurons. Consequently, dysfunction of GIRK-mediated signalling has been implicated in the pathophysiology of Alzheimer´s disease (AD). Here, we provide a quan...

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Detalles Bibliográficos
Autores principales: Alfaro-Ruiz, Rocío, Martín-Belmonte, Alejandro, Aguado, Carolina, Hernández, Félix, Moreno-Martínez, Ana Esther, Ávila, Jesús, Luján, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541655/
https://www.ncbi.nlm.nih.gov/pubmed/34681766
http://dx.doi.org/10.3390/ijms222011106