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Sarcomeres Morphology and Z-Line Arrangement Disarray Induced by Ventricular Premature Contractions through the Rac2/Cofilin Pathway

The most common ventricular premature contractions (VPCs) originate from the right ventricular outflow tract (RVOT), but the molecular mechanisms of altered cytoskeletons of VPC-induced cardiomyopathy remain unexplored. We created a RVOT bigeminy VPC pig model (n = 6 in each group). Echocardiography...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Sheng, Chang, Tzu-Hao, Ho, Wan-Chun, Chang, Shun-Fu, Chen, Yung-Lung, Chang, Shih-Tai, Chen, Huang-Chung, Pan, Kuo-Li, Chen, Mien-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541677/
https://www.ncbi.nlm.nih.gov/pubmed/34681906
http://dx.doi.org/10.3390/ijms222011244