HDAC2/3 inhibitor MI192 mitigates oligodendrocyte loss and reduces microglial activation upon injury: A potential role of epigenetics

BACKGROUND: During development, oligodendrocyte (OL) lineage cells are susceptible to injury, leading to life-long clinical neurodevelopmental deficits, which lack effective treatments. Drugs targeting epigenetic modifications that inhibit histone deacetylases (HDACs) protect from many clinical neur...

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Detalles Bibliográficos
Autores principales: Al-Griw, Mohamed A., Shmela, Mansur E., Elhensheri, Mohamed M., Bennour, Emad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of Veterinary Medicine 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541718/
https://www.ncbi.nlm.nih.gov/pubmed/34722210
http://dx.doi.org/10.5455/OVJ.2021.v11.i3.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541718/
https://www.ncbi.nlm.nih.gov/pubmed/34722210
http://dx.doi.org/10.5455/OVJ.2021.v11.i3.18

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