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Inhibition of miR-448-3p Attenuates Cerebral Ischemic Injury by Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)

BACKGROUND: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator responsible for oxidative stress in brain injury. This study aimed to investigate the potential mechanism of miR-448-3p and Nrf2 in cerebral ischemia/reperfusion (I/R) injury. METHODS: In vitro and in vivo cerebral I/R...

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Detalles Bibliográficos
Autores principales: Xu, Min, Xiang, Dingchao, Wang, Wenhua, Chen, Long, Lu, Wei, Cheng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541769/
https://www.ncbi.nlm.nih.gov/pubmed/34703235
http://dx.doi.org/10.2147/NDT.S310495