Cargando…

Inhibition of miR-448-3p Attenuates Cerebral Ischemic Injury by Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)

BACKGROUND: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator responsible for oxidative stress in brain injury. This study aimed to investigate the potential mechanism of miR-448-3p and Nrf2 in cerebral ischemia/reperfusion (I/R) injury. METHODS: In vitro and in vivo cerebral I/R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Min, Xiang, Dingchao, Wang, Wenhua, Chen, Long, Lu, Wei, Cheng, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541769/ https://www.ncbi.nlm.nih.gov/pubmed/34703235 http://dx.doi.org/10.2147/NDT.S310495

Ejemplares similares

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction()
por: Chepelev, Nikolai L., et al.
Publicado: (2013)

Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer
por: Kawasaki, Yota, et al.
Publicado: (2015)

Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases
por: Kang, Tae-Cheon
Publicado: (2020)

The Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Glaucoma: A Review
por: Wang, Mingxuan, et al.
Publicado: (2020)

Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)
por: Islam, Kazi N, et al.
Publicado: (2015)

Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes
por: Yamato, Osamu, et al.
Publicado: (2018)

Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage
por: Sun, Bin, et al.
Publicado: (2018)

Nrf2 in TIME: The Emerging Role of Nuclear Factor Erythroid 2-Related Factor 2 in the Tumor Immune Microenvironment
por: Feng, Jialin, et al.
Publicado: (2023)

PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization
por: Jankó, Laura, et al.
Publicado: (2023)

Rifampicin Attenuated Global Cerebral Ischemia Injury via Activating the Nuclear Factor Erythroid 2-Related Factor Pathway
por: Chen, Beibei, et al.
Publicado: (2016)

Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)
por: Wang, HuaiMing, et al.
Publicado: (2021)

Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis
por: Kubo, Yusuke, et al.
Publicado: (2022)

Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases
por: Francisqueti-Ferron, Fabiane Valentini, et al.
Publicado: (2019)

Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
por: Volonte, Daniela, et al.
Publicado: (2013)

The Effects of Nuclear Factor Erythroid 2 (NFE2)-Related Factor 2 (Nrf2) Activation in Preclinical Models of Peripheral Neuropathic Pain
por: Basu, Paramita, et al.
Publicado: (2022)

Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives
por: Tanase, Daniela Maria, et al.
Publicado: (2022)

Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Mediates Neuroprotection in Traumatic Brain Injury at Least in Part by Inactivating Microglia
por: Wu, Gang, et al.
Publicado: (2016)

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
por: Toth, Rachel K., et al.
Publicado: (2017)

Curcumin attenuates hypoxic-ischemic brain injury in neonatal rats through induction of nuclear factor erythroid-2-related factor 2 and heme oxygenase-1
por: Cui, Xiaolu, et al.
Publicado: (2017)

Downregulation of miR-23b by transcription factor c-Myc alleviates ischemic brain injury by upregulating Nrf2
por: Xin, Rui, et al.
Publicado: (2021)

Beneficial effects of Oltipraz, nuclear factor - erythroid – 2 - related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model
por: Polat, Emre Can, et al.
Publicado: (2018)

The effect of dietary phytochemicals on nuclear factor erythroid 2-related factor 2 (Nrf2) activation: a systematic review of human intervention trials
por: Clifford, Tom, et al.
Publicado: (2021)

Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury
por: Wu, Qi, et al.
Publicado: (2014)

Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy
por: Cui, Wenpeng, et al.
Publicado: (2017)

Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism
por: Smolková, Katarína, et al.
Publicado: (2020)

Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2‐related factor 2 pathway
por: Xie, Yan‐Zhao, et al.
Publicado: (2019)

Molecular Evolution of the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene Nrf2 in Old World Fruit Bats (Chiroptera: Pteropodidae)
por: Yin, Qiuyuan, et al.
Publicado: (2016)

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction
por: Sharma, Arpeeta, et al.
Publicado: (2017)

miR-448 targets Rab2B and is pivotal in the suppression of pancreatic cancer
por: Jin, Jing, et al.
Publicado: (2018)

Role of Nuclear Factor Erythroid 2 (Nrf2) in the Recovery of Long COVID-19 Using Natural Antioxidants: A Systematic Review
por: Muchtaridi, Muchtaridi, et al.
Publicado: (2022)

miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice
por: Hu, Xiaoping, et al.
Publicado: (2019)

Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure
por: Donnarumma, Erminia, et al.
Publicado: (2016)

Sulforaphane protects human umbilical vein endothelial cells from oxidative stress via the miR-34a/SIRT1 axis by upregulating nuclear factor erythroid-2-related factor 2
por: Li, Tao, et al.
Publicado: (2021)

L-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κB (NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)
por: Park, Seoung Ju, et al.
Publicado: (2012)

Genomic Structure and Variation of Nuclear Factor (Erythroid-Derived 2)-Like 2
por: Cho, Hye-Youn
Publicado: (2013)

Panax ginseng exerts antidepressant-like effects by suppressing neuroinflammatory response and upregulating nuclear factor erythroid 2 related factor 2 signaling in the amygdala
por: Choi, Jong Hee, et al.
Publicado: (2018)

Upregulation of antioxidant nuclear factor erythroid 2-related factor 2 and its dependent genes associated with enhancing renal ischemic preconditioning renoprotection using levosimendan and cilostazol in an ischemia/reperfusion rat model
por: Tawfik, Mona K., et al.
Publicado: (2021)

The role of nuclear factor erythroid-2-related factor 2 expression in radiocontrast-induced nephropathy
por: Kim, Ji Eun, et al.
Publicado: (2019)

Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression
por: Bansal, Yashika, et al.
Publicado: (2019)

Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders
por: Seminotti, Bianca, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_khgm6a3due27p76v98lo6io8nv