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Network pharmacology of triptolide in cancer cells: implications for transcription factor binding

Background Triptolide is an active natural product, which inhibits cell proliferation, induces cell apoptosis, suppresses tumor metastasis and improves the effect of other therapeutic treatments in several cancer cell lines by affecting multiple molecules and signaling pathways, such as caspases, he...

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Detalles Bibliográficos
Autores principales: Seo, Ean-Jeong, Dawood, Mona, Hult, Annika K., Olsson, Martin L., Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541937/
https://www.ncbi.nlm.nih.gov/pubmed/34213719
http://dx.doi.org/10.1007/s10637-021-01137-y