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Down-regulation of MAPK pathway alleviates TRPV4-mediated trigeminal neuralgia by inhibiting the activation of histone acetylation

Our objective of this study is to determine the molecular mechanism of MAPKs (mitogen activated protein kinase systems) on TRPV4 (transient receptor potential vanilloid 4)-mediated trigeminal neuralgia (TN). Partial chronic constriction injury of the infraorbital nerve (CCI-ION) ligation model was u...

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Detalles Bibliográficos
Autores principales: Liu, Weidong, Pu, Benfang, Liu, Mindi, Zhang, Xuejun, Zeng, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541954/
https://www.ncbi.nlm.nih.gov/pubmed/34499186
http://dx.doi.org/10.1007/s00221-021-06194-6