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Efficacy and safety of TAS-115, a novel oral multi-kinase inhibitor, in osteosarcoma: an expansion cohort of a phase I study

Background osteosarcoma is a rare, primary malignant bone tumour with limited available treatments for advanced or recurrent disease, resulting in a poor prognosis for patients. TAS-115 is a novel tyrosine kinase inhibitor under investigation in a phase I study in patients with solid tumours. We rep...

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Detalles Bibliográficos
Autores principales: Kawai, Akira, Naka, Norifumi, Shimomura, Akihiko, Takahashi, Shunji, Kitano, Shigehisa, Imura, Yoshinori, Yonemori, Kan, Nakatani, Fumihiko, Iwata, Shintaro, Kobayashi, Eisuke, Outani, Hidetatsu, Tamiya, Hironari, Naito, Yoichi, Yamamoto, Noboru, Doi, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541973/
https://www.ncbi.nlm.nih.gov/pubmed/34117970
http://dx.doi.org/10.1007/s10637-021-01107-4