ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis

ARID1A, encoding a subunit of SWI/SNF chromatin remodeling complex, is widely recognized as a tumor suppressor gene in multiple tumor types including liver cancer. Previous studies have demonstrated that ARID1A deficiency can cause liver cancer metastasis, possibly due to the altered chromatin organ...

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Detalles Bibliográficos
Autores principales: Shang, Xue-Ying, Shi, Yi, He, Dan-Dan, Wang, Lan, Luo, Qing, Deng, Chuan-Huai, Qu, Yu-Lan, Wang, Na, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542038/
https://www.ncbi.nlm.nih.gov/pubmed/34689165
http://dx.doi.org/10.1038/s41419-021-04291-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542038/
https://www.ncbi.nlm.nih.gov/pubmed/34689165
http://dx.doi.org/10.1038/s41419-021-04291-6

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