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ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis

ARID1A, encoding a subunit of SWI/SNF chromatin remodeling complex, is widely recognized as a tumor suppressor gene in multiple tumor types including liver cancer. Previous studies have demonstrated that ARID1A deficiency can cause liver cancer metastasis, possibly due to the altered chromatin organ...

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Detalles Bibliográficos
Autores principales:	Shang, Xue-Ying, Shi, Yi, He, Dan-Dan, Wang, Lan, Luo, Qing, Deng, Chuan-Huai, Qu, Yu-Lan, Wang, Na, Han, Ze-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542038/ https://www.ncbi.nlm.nih.gov/pubmed/34689165 http://dx.doi.org/10.1038/s41419-021-04291-6

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