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ACTL6A suppresses p21(Cip1) tumor suppressor expression to maintain an aggressive mesothelioma cancer cell phenotype

Mesothelioma is a poor prognosis cancer of the mesothelial lining that develops in response to exposure to various agents including asbestos. Actin-Like Protein 6A (ACTL6A, BAF53a) is a SWI/SNF regulatory complex protein that is elevated in cancer cells and has been implicated as a driver of cancer...

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Detalles Bibliográficos
Autores principales: Shrestha, Suruchi, Adhikary, Gautam, Naselsky, Warren, Xu, Wen, Friedberg, Joseph S., Eckert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542039/
https://www.ncbi.nlm.nih.gov/pubmed/34689163
http://dx.doi.org/10.1038/s41389-021-00362-7