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ACTL6A suppresses p21(Cip1) tumor suppressor expression to maintain an aggressive mesothelioma cancer cell phenotype
Mesothelioma is a poor prognosis cancer of the mesothelial lining that develops in response to exposure to various agents including asbestos. Actin-Like Protein 6A (ACTL6A, BAF53a) is a SWI/SNF regulatory complex protein that is elevated in cancer cells and has been implicated as a driver of cancer...
Autores principales: | Shrestha, Suruchi, Adhikary, Gautam, Naselsky, Warren, Xu, Wen, Friedberg, Joseph S., Eckert, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542039/ https://www.ncbi.nlm.nih.gov/pubmed/34689163 http://dx.doi.org/10.1038/s41389-021-00362-7 |
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