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Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

Heart failure (HF) has reached epidemic proportions in developed countries, affecting over 20 million people worldwide. Despite modern medical and device therapies, 60–70% of HF patients still die within 5 years of diagnosis as it relentlessly progresses through pervasive apoptotic loss of cardiomyo...

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Detalles Bibliográficos
Autores principales: Chunhacha, Preedakorn, Pinkaew, Decha, Sinthujaroen, Patuma, Bowles, Dawn E., Fujise, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542040/
https://www.ncbi.nlm.nih.gov/pubmed/34689154
http://dx.doi.org/10.1038/s41420-021-00692-w