Kinectin1 depletion promotes EGFR degradation via the ubiquitin-proteosome system in cutaneous squamous cell carcinoma

Depletion of kinectin1 (KTN1) provides a potential strategy for inhibiting tumorigenesis of cutaneous squamous cell carcinoma (cSCC) via reduction of epidermal growth factor receptor (EGFR) protein levels. Yet, the underlying mechanisms of KTN1 remain obscure. In this study, we demonstrate that KTN1...

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Detalles Bibliográficos
Autores principales: Ma, Ji, Ma, Shudong, Zhang, Ying, Shen, Yi, Huang, Lei, Lu, Tianhao, Wang, Lu, Wen, Yunhan, Ding, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542041/
https://www.ncbi.nlm.nih.gov/pubmed/34689164
http://dx.doi.org/10.1038/s41419-021-04276-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542041/
https://www.ncbi.nlm.nih.gov/pubmed/34689164
http://dx.doi.org/10.1038/s41419-021-04276-5

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