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Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance

Triple-negative breast cancer (TNBC) is an aggressive malignant disease that is responsible for approximately 15% of breast cancers. The standard of care relies on surgery and chemotherapy but the prognosis is poor and there is an urgent need for new therapeutic strategies. Recent in silico studies...

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Detalles Bibliográficos
Autores principales: Knab, Vanessa Maria, Gotthardt, Dagmar, Klein, Klara, Grausenburger, Reinhard, Heller, Gerwin, Menzl, Ingeborg, Prinz, Daniela, Trifinopoulos, Jana, List, Julia, Fux, Daniela, Witalisz-Siepracka, Agnieszka, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542046/
https://www.ncbi.nlm.nih.gov/pubmed/34689158
http://dx.doi.org/10.1038/s41419-021-04279-2