HES5-mediated repression of LIGHT transcription may contribute to apoptosis in hepatocytes

Non-alcoholic fatty liver disease (NAFLD) is prototypical form of metabolic syndrome and has become a global pandemic. Hepatocytes undergo apoptosis in the pathogenesis of NAFLD. We report that the lymphokine LIGHT/TNFSF14 was upregulated in the murine NAFLD livers and in hepatocytes treated with fr...

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Detalles Bibliográficos
Autores principales: Miao, Xiulian, Guo, Yan, Zeng, Sheng, Liu, Xingyu, Teng, Xiao, Li, Luyang, Hong, Wenxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542050/
https://www.ncbi.nlm.nih.gov/pubmed/34689159
http://dx.doi.org/10.1038/s41420-021-00707-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542050/
https://www.ncbi.nlm.nih.gov/pubmed/34689159
http://dx.doi.org/10.1038/s41420-021-00707-6

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