CRISPR/Cas9-mediated genome editing directed by a 5S rRNA–tRNA(Gly) hybrid promoter in the thermophilic filamentous fungus Humicola insolens

BACKGROUND: Humicola insolens is a filamentous fungus with high potential of producing neutral and heat- and alkali-resistant cellulase. However, the genetic engineering tools, particularly the genome-editing tool, are scarce, hindering the study of cellulase expression regulation in this organism....

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Detalles Bibliográficos
Autores principales: Fan, Chao, Zhang, Wei, Su, Xiaoyun, Ji, Wangli, Luo, Huiying, Zhang, Yuhong, Liu, Bo, Yao, Bin, Huang, Huoqing, Xu, Xinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542335/
https://www.ncbi.nlm.nih.gov/pubmed/34688310
http://dx.doi.org/10.1186/s13068-021-02057-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542335/
https://www.ncbi.nlm.nih.gov/pubmed/34688310
http://dx.doi.org/10.1186/s13068-021-02057-y

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