Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis

Both tumor cell-intrinsic signals and tumor cell-extrinsic signals from cells within the tumor microenvironment influence tumor cell dissemination and metastasis. The fibrillar collagen receptor tyrosine kinase (RTK) discoidin domain receptor 2 (DDR2) is essential for breast cancer metastasis in mou...

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Detalles Bibliográficos
Autores principales: Barcus, Craig E., Hwang, Priscilla Y., Morikis, Vasilios, Brenot, Audrey, Pence, Patrick, Clarke, Maria, Longmore, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542384/
https://www.ncbi.nlm.nih.gov/pubmed/34477203
http://dx.doi.org/10.1242/jcs.258431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542384/
https://www.ncbi.nlm.nih.gov/pubmed/34477203
http://dx.doi.org/10.1242/jcs.258431

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