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Fission yeast TOR complex 1 phosphorylates Psk1 through an evolutionarily conserved interaction mediated by the TOS motif

TOR complex 1 (TORC1) is a multi-subunit protein kinase complex that controls cellular growth in response to environmental cues. The regulatory subunits of mammalian TORC1 (mTORC1) include RAPTOR (also known as RPTOR), which recruits mTORC1 substrates, such as S6K1 (also known as RPS6KB1) and 4EBP1...

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Detalles Bibliográficos
Autores principales: Morozumi, Yuichi, Hishinuma, Ai, Furusawa, Suguru, Sofyantoro, Fajar, Tatebe, Hisashi, Shiozaki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542387/
https://www.ncbi.nlm.nih.gov/pubmed/34499159
http://dx.doi.org/10.1242/jcs.258865