Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice

Compared to other RV species, RV-C has been associated with more severe respiratory illness and is more likely to occur in children with a history of asthma or who develop asthma. We therefore inoculated six-day-old mice with sham, RV-A1B, or RV-C15. Inflammasome priming and activation were assessed...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Mingyuan, Ishikawa, Tomoko, Stroupe, Claudia C., Breckenridge, Haley A., Bentley, J. Kelley, Hershenson, Marc B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542611/
https://www.ncbi.nlm.nih.gov/pubmed/34354243
http://dx.doi.org/10.1038/s41385-021-00436-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542611/
https://www.ncbi.nlm.nih.gov/pubmed/34354243
http://dx.doi.org/10.1038/s41385-021-00436-0

Ejemplares similares