Cargando…
Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice
Compared to other RV species, RV-C has been associated with more severe respiratory illness and is more likely to occur in children with a history of asthma or who develop asthma. We therefore inoculated six-day-old mice with sham, RV-A1B, or RV-C15. Inflammasome priming and activation were assessed...
Autores principales: | Han, Mingyuan, Ishikawa, Tomoko, Stroupe, Claudia C., Breckenridge, Haley A., Bentley, J. Kelley, Hershenson, Marc B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542611/ https://www.ncbi.nlm.nih.gov/pubmed/34354243 http://dx.doi.org/10.1038/s41385-021-00436-0 |
Ejemplares similares
-
Rhinovirus C Infection Induces Type 2 Innate Lymphoid Cell Expansion and Eosinophilic Airway Inflammation
por: Rajput, Charu, et al.
Publicado: (2021) -
Construction of a recombinant rhinovirus accommodating fluorescent marker expression
por: Han, Mingyuan, et al.
Publicado: (2018) -
M2 Macrophages promote IL-33 expression, ILC2 expansion and mucous metaplasia in response to early life rhinovirus infections
por: Han, Mingyuan, et al.
Publicado: (2022) -
Rhinovirus-Induced Exacerbations of Asthma and COPD
por: Hershenson, Marc B.
Publicado: (2013) -
Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma
por: Hong, Jun Young, et al.
Publicado: (2014)