PC Deficiency Testing: Thrombin-Thrombomodulin as PC Activator and Aptamer-Based Enzyme Capturing Increase Diagnostic Accuracy

Protein C (PC) activity tests are routinely performed in a thrombophilia workup to screen for PC deficiency. Currently used tests combine conversion of PC to activated PC (APC) by the snake venom Protac with subsequent APC detection through hydrolysis of a chromogenic peptide substrate or prolongati...

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Detalles Bibliográficos
Autores principales: Reda, Sara, Rühl, Heiko, Witkowski, Jana, Müller, Jens, Pavlova, Anna, Oldenburg, Johannes, Pötzsch, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542722/
https://www.ncbi.nlm.nih.gov/pubmed/34708097
http://dx.doi.org/10.3389/fcvm.2021.755281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542722/
https://www.ncbi.nlm.nih.gov/pubmed/34708097
http://dx.doi.org/10.3389/fcvm.2021.755281

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