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Irinotecan-Induced Steatohepatitis: Current Insights

The hepatotoxicity of irinotecan is drawing wide concern nowadays due to the widespread use of this chemotherapeutic against various solid tumors, particularly metastatic colorectal cancer. Irinotecan-induced hepatotoxicity mainly manifests as transaminase increase and steatosis with or without tran...

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Detalles Bibliográficos
Autores principales: Han, Jun, Zhang, Jing, Zhang, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542761/
https://www.ncbi.nlm.nih.gov/pubmed/34707997
http://dx.doi.org/10.3389/fonc.2021.754891