Targeting BRCA and DNA Damage Repair Genes in GI Cancers: Pathophysiology and Clinical Perspectives

Mutated germline alleles in the DNA damage repair (DDR) genes “breast cancer gene 1” (BRCA1) and BRCA2 have originally been identified as major susceptibility genes in breast and ovarian cancers. With the establishment and approval of more cost-effective gene sequencing methods, germline and somatic...

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Detalles Bibliográficos
Autores principales: Zimmer, Kai, Kocher, Florian, Puccini, Alberto, Seeber, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542868/
https://www.ncbi.nlm.nih.gov/pubmed/34707985
http://dx.doi.org/10.3389/fonc.2021.662055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542868/
https://www.ncbi.nlm.nih.gov/pubmed/34707985
http://dx.doi.org/10.3389/fonc.2021.662055

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