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Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice

The efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is limited by the occurrence of acute and chronic graft-versus-host disease (GVHD). We have recently demonstrated that obesity results in exacerbated acute gastrointestinal GVHD in both mouse models and clinical outcomes...

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Detalles Bibliográficos
Autores principales: Khuat, Lam T., Vick, Logan V., Choi, Eunju, Dunai, Cordelia, Merleev, Alexander A., Maverakis, Emanual, Blazar, Bruce R., Monjazeb, Arta M., Murphy, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542879/
https://www.ncbi.nlm.nih.gov/pubmed/34707616
http://dx.doi.org/10.3389/fimmu.2021.752484