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Characterization of the Infant Immune System and the Influence and Immunogenicity of BCG Vaccination in Infant and Adult Rhesus Macaques

In many countries where tuberculosis (TB) is endemic, the Bacillus Calmette–Guérin (BCG) vaccine is given as close to birth as possible to protect infants and children from severe forms of TB. However, BCG has variable efficacy and is not as effective against adult pulmonary TB. At present, most ani...

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Detalles Bibliográficos
Autores principales: Sarfas, Charlotte, White, Andrew D., Sibley, Laura, Morrison, Alexandra L., Gullick, Jennie, Lawrence, Steve, Dennis, Mike J., Marsh, Philip D., Fletcher, Helen A., Sharpe, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542880/
https://www.ncbi.nlm.nih.gov/pubmed/34707617
http://dx.doi.org/10.3389/fimmu.2021.754589