A Developmental Role of the Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Lung Disease Pathogenesis

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein is a cAMP-activated anion channel that is critical for regulating fluid and ion transport across the epithelium. This process is disrupted in CF epithelia, and patients harbouring CF-causing mutations experience reduced lung...

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Detalles Bibliográficos
Autores principales: Huang, Elena N., Quach, Henry, Lee, Jin-A, Dierolf, Joshua, Moraes, Theo J., Wong, Amy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542926/
https://www.ncbi.nlm.nih.gov/pubmed/34708042
http://dx.doi.org/10.3389/fcell.2021.742891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542926/
https://www.ncbi.nlm.nih.gov/pubmed/34708042
http://dx.doi.org/10.3389/fcell.2021.742891

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