Intranasal Vaccination With Recombinant Antigen-FLIPr Fusion Protein Alone Induces Long-Lasting Systemic Antibody Responses and Broad T Cell Responses

A simple formulation is urgently needed for mucosal vaccine development. We employed formyl peptide receptor-like 1 inhibitory protein (FLIPr), an FcγR antagonist secreted by Staphylococcus aureus, as a vector to target ovalbumin (OVA) to dendritic cells (DCs) via intranasal administration. Our resu...

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Detalles Bibliográficos
Autores principales: Hsieh, Ming-Shu, Hsu, Chia-Wei, Tu, Ling-Ling, Chai, Kit Man, Yu, Li-Lu, Wu, Chiao-Chieh, Chen, Mei-Yu, Chiang, Chen-Yi, Liu, Shih-Jen, Liao, Ching-Len, Chen, Hsin-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543008/
https://www.ncbi.nlm.nih.gov/pubmed/34707615
http://dx.doi.org/10.3389/fimmu.2021.751883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543008/
https://www.ncbi.nlm.nih.gov/pubmed/34707615
http://dx.doi.org/10.3389/fimmu.2021.751883

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