Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals

To assess the relative contribution of opsonisation by antibodies, classical and alternative complement pathways to pneumococcal phagocytosis, we analyzed killing of pneumococci by human blood leukocytes collected from vaccine-naïve and PCV13-vaccinated subjects. With serotype 4 pneumococci as model...

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Detalles Bibliográficos
Autores principales: Muri, Lukas, Ispasanie, Emma, Schubart, Anna, Thorburn, Christine, Zamurovic, Natasa, Holbro, Thomas, Kammüller, Michael, Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543009/
https://www.ncbi.nlm.nih.gov/pubmed/34707606
http://dx.doi.org/10.3389/fimmu.2021.732146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543009/
https://www.ncbi.nlm.nih.gov/pubmed/34707606
http://dx.doi.org/10.3389/fimmu.2021.732146

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