Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain

The unfolded protein response (UPR) is involved in the pathogenesis of metabolic disorders, yet whether variations in the UPR among individuals influence the propensity for metabolic disease remains unexplored. Using outbred deer mice as a model, we show that the intensity of UPR in fibroblasts isol...

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Detalles Bibliográficos
Autores principales: Zhang, Youwen, Lim, Chang-uk, Sikirzhytski, Vitali, Naderi, Asieh, Chatzistamou, Ioulia, Kiaris, Hippokratis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543066/
https://www.ncbi.nlm.nih.gov/pubmed/34661243
http://dx.doi.org/10.1242/dmm.049113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543066/
https://www.ncbi.nlm.nih.gov/pubmed/34661243
http://dx.doi.org/10.1242/dmm.049113

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