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Mapping Function from Dynamics: Future Challenges for Network-Based Models of Protein Structures

Proteins fulfill complex and diverse biological functions through the controlled atomic motions of their structures (functional dynamics). The protein composition is given by its amino-acid sequence, which was assumed to encode the function. However, the discovery of functional sequence variants pro...

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Detalles Bibliográficos
Autores principales: Pacini, Lorenza, Dorantes-Gilardi, Rodrigo, Vuillon, Laurent, Lesieur, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543124/
https://www.ncbi.nlm.nih.gov/pubmed/34708077
http://dx.doi.org/10.3389/fmolb.2021.744646