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Mapping Function from Dynamics: Future Challenges for Network-Based Models of Protein Structures
Proteins fulfill complex and diverse biological functions through the controlled atomic motions of their structures (functional dynamics). The protein composition is given by its amino-acid sequence, which was assumed to encode the function. However, the discovery of functional sequence variants pro...
Autores principales: | Pacini, Lorenza, Dorantes-Gilardi, Rodrigo, Vuillon, Laurent, Lesieur, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543124/ https://www.ncbi.nlm.nih.gov/pubmed/34708077 http://dx.doi.org/10.3389/fmolb.2021.744646 |
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