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A Super-Resolved View of the Alzheimer’s Disease-Related Amyloidogenic Pathway in Hippocampal Neurons

BACKGROUND: Processing of the amyloid-β protein precursor (AβPP) is neurophysiologically important due to the resulting fragments that regulate synapse biology, as well as potentially harmful due to generation of the 42 amino acid long amyloid β-peptide (Aβ(42)), which is a key player in Alzheimer’s...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Gao, Yang, Winblad, Bengt, Tjernberg, Lars O., Schedin-Weiss, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543249/
https://www.ncbi.nlm.nih.gov/pubmed/34366358
http://dx.doi.org/10.3233/JAD-215008